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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP49
All Species:
8.48
Human Site:
S316
Identified Species:
18.67
UniProt:
Q70CQ1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70CQ1
NP_061031.2
688
79198
S316
N
S
S
A
T
E
L
S
L
R
N
D
R
A
E
Chimpanzee
Pan troglodytes
XP_518467
759
87316
S387
N
S
S
A
T
E
L
S
L
R
N
D
R
A
E
Rhesus Macaque
Macaca mulatta
XP_001085246
657
75261
L292
D
P
S
K
T
E
H
L
F
P
K
A
T
N
G
Dog
Lupus familis
XP_532134
681
77708
A310
A
S
A
A
E
L
S
A
R
S
G
G
A
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9L4
685
78254
S313
S
S
S
A
A
E
L
S
V
R
S
V
R
A
Q
Rat
Rattus norvegicus
B2GUX4
565
62681
V212
L
L
L
G
S
G
H
V
G
L
R
N
L
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510004
1411
160789
P331
S
V
S
D
S
V
I
P
M
Q
E
N
P
E
K
Chicken
Gallus gallus
O57429
357
40913
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392160
541
61414
L188
K
E
K
K
V
V
G
L
R
N
L
G
N
T
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792596
510
58338
K157
R
K
R
M
K
R
E
K
R
D
D
S
F
F
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
W118
D
A
I
L
A
K
Y
W
D
D
V
C
T
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
90.6
92.1
N.A.
90.4
22.9
N.A.
31.1
20.9
N.A.
N.A.
N.A.
N.A.
31.3
N.A.
25.5
Protein Similarity:
100
90.5
92
93.9
N.A.
94.1
38
N.A.
38.5
32.4
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
40.1
P-Site Identity:
100
100
20
13.3
N.A.
60
0
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
26.6
26.6
N.A.
86.6
13.3
N.A.
53.3
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
37
19
0
0
10
0
0
0
10
10
28
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% C
% Asp:
19
0
0
10
0
0
0
0
10
19
10
19
0
0
0
% D
% Glu:
0
10
0
0
10
37
10
0
0
0
10
0
0
19
19
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% F
% Gly:
0
0
0
10
0
10
10
0
10
0
10
19
0
10
10
% G
% His:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
10
19
10
10
0
10
0
0
10
0
0
10
10
% K
% Leu:
10
10
10
10
0
10
28
19
19
10
10
0
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
19
0
0
0
0
0
0
0
0
10
19
19
10
10
10
% N
% Pro:
0
10
0
0
0
0
0
10
0
10
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
10
0
10
0
0
10
0
0
28
28
10
0
28
0
0
% R
% Ser:
19
37
46
0
19
0
10
28
0
10
10
10
0
0
0
% S
% Thr:
0
0
0
0
28
0
0
0
0
0
0
0
19
10
10
% T
% Val:
0
10
0
0
10
19
0
10
10
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _